AMPK as a mediator of hormonal signalling

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AMPK as a mediator of hormonal signalling.

AMP-activated protein kinase (AMPK) is a key molecular player in energy homeostasis at both cellular and whole-body levels. AMPK has been shown to mediate the metabolic effects of hormones such as leptin, ghrelin, adiponectin, glucocorticoids and insulin as well as cannabinoids. Generally, activated AMPK stimulates catabolic pathways (glycolysis, fatty acid oxidation and mitochondrial biogenesi...

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ژورنال

عنوان ژورنال: Journal of Molecular Endocrinology

سال: 2009

ISSN: 0952-5041,1479-6813

DOI: 10.1677/jme-09-0063